Custom antibody production services allow researchers to tailor their projects to meet specific needs with fast turnaround and high quality. Sino Biological provides one-stop services from antigen design and immunization to antibody development, characterization, and purification.
A typical antibody project starts with sourcing protein antigens. These can be derived from cell cultures, tissues, body fluids like semen or amniotic fluid, and even synthetic peptides. In order to ensure that the antigens will produce a satisfactory antibody response, they have to be tested in animals first.
Comprehensive Custom Antibody Production Services for Researchers
The animal must be injected with the chosen antigen multiple times in order to induce antibodies that are capable of binding to it. This process is known as immunization and can take a few weeks to complete. Once the immunization process is completed, the antibody produced by the animal must then be isolated from other cells within the blood and purified.
The isolated antibody can be categorized into polyclonal or monoclonal. Monoclonal antibodies typically require longer timelines to produce and are more expensive per milligram. Polyclonal antibodies on the other hand are typically cheaper to produce and have shorter lead times. This makes them more suitable for a wide range of applications. Polyclonal antibodies can be made in various host species such as rabbit, camel, llama and alpaca. These host species are ideal due to their size and easy handling characteristics as well as their ability to produce higher titers of high-affinity antibodies. This is particularly useful for targeting cryptic antigens.…